Department of Veterinary Pathobiology

Leslie A. Lyons
Gilbreath-McLorn Endowed Professor of Comparative Medicine

  • B.S., University of Pittsburgh
  • M.S., University of Pittsburgh
  • Ph.D., University of Pittsburgh

Building Address: E109 Vet Med Building
Phone Number: 573-882-9777
Email: Lyonsla@Missouri.edu

Research Emphasis: Research focuses on genetic aspects of domestic cats, including inherited diseases, traits and population dynamics, which are implied to genetic disease studies, translational medicine, genetic testing, and forensic applications. The Lyons laboratory maintains a research colony of cats with genetic traits and has a variety of projects with veterinary clinicians to define and describe heritable diseases and traits.

Laboratory: Lyons Feline & Comparative Genetics
Lab Phone: 573-884 -2287 (4-CATS)

Graduate Groups:

Genetics Area Program
Comparative Medicine Area Program
Veterinary Pathobiology

Publications by topic:

99 Lives Cat Genome Sequencing Initiative

Mauler DA, Gandolfi B, Reinero CR, O'Brien DP, Spooner JL, Lyons LA; 99 Lives Consortium. Precision Medicine in Cats: Novel Niemann-Pick Type C1 Diagnosed by Whole-Genome Sequencing. J Vet Intern Med. 2017 Feb 24. doi: 10.1111/jvim.14599. [Epub ahead of print] PubMed PMID: 28233346.

Aberdein D, Munday JS, Gandolfi B, Dittmer KE, Malik R, Garrick DJ, Lyons LA; 99 Lives Consortium. A FAS-ligand variant associated with autoimmune lymphoproliferative syndrome in cats. Mamm Genome. 2017 Feb;28(1-2):47-55. doi:10.1007/s00335-016-9668-1. Erratum in: Mamm Genome. 2017 Jan 18; PubMed PMID:27770190.

Lyons LA, Creighton EK, Alhaddad H, Beale HC, Grahn RA, Rah H, Maggs DJ, Helps CR, Gandolfi B. Whole genome sequencing in cats, identifies new models for blindness in AIPL1 and somite segmentation in HES7. BMC Genomics. 2016 Mar 31;17:265. doi: 10.1186/s12864-016-2595-4. PubMed PMID: 27030474; PubMed Central PMCID: PMC4815086.

Gandolfi B, Grahn RA, Creighton EK, Williams DC, Dickinson PJ, Sturges BK, Guo LT, Shelton GD, Leegwater PA, Longeri M, Malik R, Lyons LA. COLQ variant associated with Devon Rex and Sphynx feline hereditary myopathy. Anim Genet. 2015 Dec;46(6):711-5. doi: 10.1111/age.12350. PubMed PMID: 26374066; PubMed Central PMCID: PMC4637250.

Cat Diseases and Clinical Studies

Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, Wallecha A, Huebner M, Paterson Y, O'Connor D, Treml LS, Stannard JP, Cook JL, Jacobs M, Wyckoff GJ, Likins L, Sabbagh U, Skaff A, Guloy AS, Hays HD, LeBlanc AK, Coates JR, Katz ML, Lyons LA, Johnson GC, Johnson GS, O'Brien DP, Duan D, Calvet JP, Gandolfi B, Baron DA, Weiss ML, Webster DA, Karanu FN, Robb EJ, Harman RJ. A One Health overview, facilitating advances in comparative medicine and translational research. Clin Transl Med. 2016 Aug;5(Suppl 1):26. doi: 10.1186/s40169-016-0107-4. PubMed PMID: 27558513; PubMed Central PMCID: PMC4996801.

Lyons LA, Grahn RA, Genova F, Beccaglia M, Hopwood JJ, Longeri M. Mucopolysaccharidosis VI in cats - clarification regarding genetic testing. BMC Vet Res. 2016 Jul 2;12(1):136. doi: 10.1186/s12917-016-0764-y. PubMed PMID:27370326; PubMed Central PMCID: PMC4930586.

Gandolfi B, Grahn RA, Gustafson NA, Proverbio D, Spada E, Adhikari B, Cheng J, Andrews G, Lyons LA, Helps CR. A Novel Variant in CMAH Is Associated with Blood Type AB in Ragdoll Cats. PLoS One. 2016 May 12;11(5):e0154973. doi:10.1371/journal.pone.0154973. PubMed PMID: 27171395; PubMed Central PMCID: PMC4865243.

Gandolfi B, Alamri S, Darby WG, Adhikari B, Lattimer JC, Malik R, Wade CM, Lyons LA, Cheng J, Bateman JF, McIntyre P, Lamandé SR, Haase B. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. Osteoarthritis Cartilage. 2016 Aug;24(8):1441-50. doi: 10.1016/j.joca.2016.03.019. PubMed PMID:27063440.

Keating MK, Sturges BK, Sisó S, Wisner ER, Creighton EK, Lyons LA. Characterization of an Inherited Neurologic Syndrome in Toyger Cats with Forebrain Commissural Malformations, Ventriculomegaly and Interhemispheric Cysts. J Vet Intern Med. 2016 Mar-Apr;30(2):617-26. doi: 10.1111/jvim.13836. PubMed PMID: 26846816; PubMed Central PMCID: PMC4913598.

Lyons LA, Erdman CA, Grahn RA, Hamilton MJ, Carter MJ, Helps CR, Alhaddad H, Gandolfi B. Aristaless-Like Homeobox protein 1 (ALX1) variant associated with craniofacial structure and frontonasal dysplasia in Burmese cats. Dev Biol. 2016 Jan 15;409(2):451-8. doi: 10.1016/j.ydbio.2015.11.015. PubMed PMID: 26610632; PubMed Central PMCID: PMC4724490.

Ofri R, Reilly CM, Maggs DJ, Fitzgerald PG, Shilo-Benjamini Y, Good KL, Grahn RA, Splawski DD, Lyons LA. Characterization of an Early-Onset, Autosomal Recessive, Progressive Retinal Degeneration in Bengal Cats. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5299-308. doi: 10.1167/iovs.15-16585. PMID: 26258614

Malik R, Musca FJ, Gunew MN, Menrath VH, Simpson C, Culvenor J, Grahn RA, Helps C, Lyons LA, Gandolfi B. Periodic hypokalaemic polymyopathy in Burmese and closely related cats: a review including the latest genetic data. J Feline Med Surg. 2015 May;17(5):417-26. doi: 10.1177/1098612X15581135. Review. PMID: 25896241

Lyons LA. DNA mutations of the cat: the good, the bad and the ugly. J Feline Med Surg. 2015 Mar;17(3):203-19. doi: 10.1177/1098612X15571878. Review. PMID: 25701860

Jones BR, Little S, Lyons LA, Malik R, Nicholas F, O'Brien DP, Pedersen NC. Understanding genetics: why should vets care? J Feline Med Surg. 2015 Mar;17(3):201-2. doi: 10.1177/1098612X15571877. PMID: 25701859 [PubMed - indexed for MEDLINE]

Nivy R, Lyons LA, Aroch I, Segev G.J Polycystic kidney disease in four British shorthair cats with successful treatment of bacterial cyst infection. Small Anim Pract. 2015 Sep;56(9):585-9. doi: 10.1111/jsap.12327. PMID: 25677715

Pollard RE, Koehne AL, Peterson CB, Lyons LA. Japanese Bobtail: vertebral morphology and genetic characterization of an established cat breed. J Feline Med Surg. 2014. doi: 10.1177/1098612X14558147. PubMed PMID: 25488973.

Gandolfi B, Daniel RJ, O'Brien DP, Guo LT, Youngs MD, Leach SB, Jones BR, Shelton GD, Lyons LA. A Novel Mutation in CLCN1 Associated with Feline Myotonia Congenita. PloS one. 2014;9(10):e109926. doi: 10.1371/journal.pone.0109926. PubMed PMID: 25356766; PubMed Central PMCID: PMC4214686.

Alhaddad H, Gandolfi B, Grahn RA, Rah HC, Peterson CB, Maggs DJ, Good KL, Pedersen NC, Lyons LA. Genome-wide association and linkage analyses localize a progressive retinal atrophy locus in Persian cats. Mamm Genome. 2014;25(7-8):354-62. doi: 10.1007/s00335-014-9517-z. PubMed PMID: 24777202; PubMed Central PMCID: PMC4105591.

Longeri M, Ferrari P, Knafelz P, Mezzelani A, Marabotti A, Milanesi L, Pertica G, Polli M, Brambilla PG, Kittleson M, Lyons LA, Porciello F. Myosin-binding protein C DNA variants in domestic cats (A31P, A74T, R820W) and their association with hypertrophic cardiomyopathy. J Vet Intern Med. 2013;27(2):275-85. doi: 10.1111/jvim.12031. PubMed PMID: 23323744; PubMed Central PMCID: PMC3602388.

Langley-Hobbs SJ, Bailey SJ, Casal M, Lyons LA. Patellar fractures in cats. The Veterinary record. 2013;172(3):83-4. Epub 2013/01/22. doi: 10.1136/vr.f337. PubMed PMID: 23335690.

Grahn RA, Grahn JC, Penedo MC, Helps CR, Lyons LA. Erythrocyte pyruvate kinase deficiency mutation identified in multiple breeds of domestic cats. BMC veterinary research. 2012;8:207. Epub 2012/11/01. doi: 10.1186/1746-6148-8-207. PubMed PMID: 23110753; PubMed Central PMCID: PMC3534511.

Grahn RA, Ellis MR, Grahn JC, Lyons LA. A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA. J Feline Med Surg. 2012;14(8):587-90. Epub 2012/05/04. doi: 10.1177/1098612X12446637. PubMed PMID: 22553308.

Gandolfi B, Gruffydd-Jones TJ, Malik R, Cortes A, Jones BR, Helps CR, Prinzenberg EM, Erhardt G, Lyons LA. First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. PloS one. 2012;7(12):e53173. Epub 2013/01/04. doi: 10.1371/journal.pone.0053173. PubMed PMID: 23285264; PubMed Central PMCID: PMC3532348.

Martin PT, Shelton GD, Dickinson PJ, Sturges BK, Xu R, LeCouteur RA, Guo LT, Grahn RA, Lo HP, North KN, Malik R, Engvall E, Lyons LA. Muscular dystrophy associated with alpha-dystroglycan deficiency in Sphynx and Devon Rex cats. Neuromuscul Disord. 2008;18(12):942-52. Epub 2008/11/08. doi: 10.1016/j.nmd.2008.08.002. PubMed PMID: 18990577; PubMed Central PMCID: PMC2646259.

Bighignoli B, Niini T, Grahn RA, Pedersen NC, Millon LV, Polli M, Longeri M, Lyons LA. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) mutations associated with the domestic cat AB blood group. BMC genetics. 2007;8:27. Epub 2007/06/08. doi: 10.1186/1471-2156-8-27. PubMed PMID: 17553163; PubMed Central PMCID: PMC1913925.

Lyons LA, Biller DS, Erdman CA, Lipinski MJ, Young AE, Roe BA, Qin B, Grahn RA. Feline polycystic kidney disease mutation identified in PKD1. J Am Soc Nephrol. 2004;15(10):2548-55. Epub 2004/10/07. doi: 10.1097/01.ASN.0000141776.38527.BB. PubMed PMID: 15466259.

Louwerens M, London CA, Pedersen NC, Lyons LA. Feline lymphoma in the post-feline leukemia virus era. J Vet Intern Med. 2005;19(3):329-35. Epub 2005/06/16. PubMed PMID: 15954547.

Rah H, Maggs DJ, Blankenship TN, Narfstrom K, Lyons LA. Early-onset, autosomal recessive, progressive retinal atrophy in Persian cats. Invest Ophthalmol Vis Sci. 2005;46(5):1742-7. Epub 2005/04/27. doi: 10.1167/iovs.04-1019. PubMed PMID: 15851577.

Infectious Peritonitis (FIP)

Pedersen NC, Liu H, Durden M, Lyons LA. Natural resistance to experimental feline infectious peritonitis virus infection is decreased rather than increased by positive genetic selection. Vet Immunol Immunopathol. 2016 Mar;171:17-20. doi:10.1016/j.vetimm.2016.01.002. PubMed PMID: 26964713.

Pedersen NC, Liu H, Gandolfi B, Lyons LA. The influence of age and genetics on natural resistance to experimentally induced feline infectious peritonitis. Veterinary immunology and immunopathology. 2014. doi: 10.1016/j.vetimm.2014.09.001. PubMed PMID: 25265870.

Golovko L, Lyons LA, Liu H, Sorensen A, Wehnert S, Pedersen NC. Genetic susceptibility to feline infectious peritonitis in Birman cats. Virus research. 2013;175(1):58-63. doi: 10.1016/j.virusres.2013.04.006. PubMed PMID: 23619280.

Pedersen NC, Allen CE, Lyons LA. Pathogenesis of feline enteric coronavirus infection. J Feline Med Surg. 2008;10(6):529-41. Epub 2008/06/10. doi: 10.1016/j.jfms.2008.02.006. PubMed PMID: 18538604.

Cat Reproduction

Lambo CA, Grahn RA, Lyons LA, Bateman H, Newsom J, Swanson WF. Comparative fertility of freshly collected vs frozen-thawed semen with laparoscopic oviductal artificial insemination in domestic cats. Reproduction in domestic animals = Zuchthygiene. 2012;47 Suppl 6:284-8. Epub 2013/02/12. doi: 10.1111/rda.12038. PubMed PMID: 23279520.

Schlafer DH, Valentine B, Fahnestock G, Froenicke L, Grahn RA, Lyons LA, Meyers-Wallen VN. A case of SRY-positive 38,XY true hermaphroditism (XY sex reversal) in a cat. Vet Pathol. 2011;48(4):817-22. Epub 2010/09/24. doi: 10.1177/0300985810382093. PubMed PMID: 20861501; PubMed Central PMCID: PMC3271121.

Gomez MC, Pope CE, Kutner RH, Ricks DM, Lyons LA, Ruhe M, Dumas C, Lyons J, Lopez M, Dresser BL, Reiser J. Nuclear transfer of sand cat cells into enucleated domestic cat oocytes is affected by cryopreservation of donor cells. Cloning Stem Cells. 2008;10(4):469-83. Epub 2008/09/18. doi: 10.1089/clo.2008.0021. PubMed PMID: 18795868.

Gomez MC, Pope CE, Giraldo A, Lyons LA, Harris RF, King AL, Cole A, Godke RA, Dresser BL. Birth of African Wildcat cloned kittens born from domestic cats. Cloning Stem Cells. 2004;6(3):247-58. Epub 2005/01/27. doi: 10.1089/clo.2004.6.247. PubMed PMID: 15671671.

Shin T, Kraemer D, Pryor J, Liu L, Rugila J, Howe L, Buck S, Murphy K, Lyons L, Westhusin M. A cat cloned by nuclear transplantation. Nature. 2002;415(6874):859. PubMed PMID: 11859353.

Cat Colors and Phenotypic Traits

Gustafson NA, Gandolfi B, Lyons LA. Not another type of potato: MC1R and the russet coloration of Burmese cats. Anim Genet. 2017 Feb;48(1):116-120. doi:10.1111/age.12505. PubMed PMID: 27671997.

Gershony LC, Penedo MC, Davis BW, Murphy WJ, Helps CR, Lyons LA. Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. Anim Genet. 2014;45(6):893-7. doi: 10.1111/age.12206. PubMed PMID: 25143047; PubMed Central PMCID: PMC4211939.

Gandolfi B, Alhaddad H, Affolter VK, Brockman J, Haggstrom J, Joslin SE, Koehne AL, Mullikin JC, Outerbridge CA, Warren WC, Lyons LA. To the Root of the Curl: A Signature of a Recent Selective Sweep Identifies a Mutation That Defines the Cornish Rex Cat Breed. PloS one. 2013;8(6):e67105. Epub 2013/07/05. doi: 10.1371/journal.pone.0067105. PubMed PMID: 23826204; PubMed Central PMCID: PMC3694948.

Buckingham KJ, McMillin MJ, Brassil MM, Shively KM, Magnaye KM, Cortes A, Weinmann AS, Lyons LA, Bamshad MJ. Multiple mutant T alleles cause haploinsufficiency of Brachyury and short tails in Manx cats. Mamm Genome. 2013;24(9-10):400-8. doi: 10.1007/s00335-013-9471-1. PubMed PMID: 23949773.

Gandolfi B, Outerbridge CA, Beresford LG, Myers JA, Pimentel M, Alhaddad H, Grahn JC, Grahn RA, Lyons LA. The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mamm Genome. 2010;21(9-10):509-15. Epub 2010/10/19. doi: 10.1007/s00335-010-9290-6. PubMed PMID: 20953787; PubMed Central PMCID: PMC2974189.

Lyons LA, Imes DL, Rah HC, Grahn RA. Tyrosinase mutations associated with Siamese and Burmese patterns in the domestic cat (Felis catus). Anim Genet. 2005;36(2):119-26. Epub 2005/03/18. doi: 10.1111/j.1365-2052.2005.01253.x. PubMed PMID: 15771720.

Lyons LA , Foe IT, Rah HC, Grahn RA. Chocolate coated cats: TYRP1 mutations for brown color in domestic cats. Mamm Genome. 2005;16(5):356-66. Epub 2005/08/18. PubMed PMID: 16104383.

Imes DL, Geary LA, Grahn RA, Lyons LA. Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation. Anim Genet. 2006;37(2):175-8. Epub 2006/04/01. doi: 10.1111/j.1365-2052.2005.01409.x. PubMed PMID: 16573534; PubMed Central PMCID: PMC1464423.

Forensics and Population Studies (Cat Breeds and Races)

Brooks A, Creighton EK, Gandolfi B, Khan R, Grahn RA, Lyons LA. SNP Miniplexes for Individual Identification of Random-Bred Domestic Cats. J Forensic Sci. 2016 May;61(3):594-606. doi: 10.1111/1556-4029.13026. PubMed PMID: 27122395; PubMed Central PMCID: PMC5019183.

Arcieri M, Agostinelli G, Gray Z, Spadaro A, Lyons LA, Webb KM. Establishing a database of Canadian feline mitotypes for forensic use. Forensic Sci Int Genet. 2016 May;22:169-74. doi: 10.1016/j.fsigen.2016.02.013. PubMed PMID: 26971852.

Lyons LA, Grahn RA, Kun TJ, Netzel LR, Wictum EE, Halverson JL. Acceptance of domestic cat mitochondrial DNA in a criminal proceeding. Forensic science international Genetics. 2014;13:61-7. doi: 10.1016/j.fsigen.2014.07.007. PubMed PMID: 25086413; PubMed Central PMCID: PMC4186908.

Grahn RA, Alhaddad H, Alves PC, Randi E, Waly NE, Lyons LA. Feline mitochondrial DNA sampling for forensic analysis: When enough is enough! Forensic science international Genetics. 2014;16C:52-7. doi: 10.1016/j.fsigen.2014.11.017. PubMed PMID: 25531059.

Kurushima JD, Lipinski MJ, Gandolfi B, Froenicke L, Grahn JC, Grahn RA, Lyons LA. Variation of cats under domestication: genetic assignment of domestic cats to breeds and worldwide random-bred populations. Anim Genet. 2013;44(3):311-24. Epub 2012/11/23. doi: 10.1111/age.12008. PubMed PMID: 23171373; PubMed Central PMCID: PMC3594446.

Kun T, Lyons LA, Sacks BN, Ballard RE, Lindquist C, Wictum EJ. Developmental validation of Mini-DogFiler for degraded canine DNA. Forensic science international Genetics. 2013;7(1):151-8. Epub 2012/10/09. doi: 10.1016/j.fsigen.2012.09.002. PubMed PMID: 23040244.

Grahn RA, Huang TI-T, Lyons LA. Impact of allogrooming in domestic cats (Felis silvestris catus) on mitochondrial DNA profiling of shed hairs. Open Forensic Science Journal. 2013;6:12-9. doi: 10.2174/1874402801306010012.

Kurushima JD, Ikram S, Knudsen J, Bleiberg E, Grahn RA, Lyons LA. Cats of the Pharaohs: Genetic Comparison of Egyptian Cat Mummies to their Feline Contemporaries. Journal of archaeological science. 2012;39(10):3217-23. Epub 2012/08/28. doi: 10.1016/j.jas.2012.05.005. PubMed PMID: 22923880; PubMed Central PMCID: PMC3426309.

Grahn RA, Kurushima JD, Billings NC, Grahn JC, Halverson JL, Hammer E, Ho CK, Kun TJ, Levy JK, Lipinski MJ, Mwenda JM, Ozpinar H, Schuster RK, Shoorijeh SJ, Tarditi CR, Waly NE, Wictum EJ, Lyons LA. Feline non-repetitive mitochondrial DNA control region database for forensic evidence. Forensic science international Genetics. 2011;5(1):33-42. Epub 2010/05/12. doi: 10.1016/j.fsigen.2010.01.013. PubMed PMID: 20457082; PubMed Central PMCID: PMC2921450.

Lipinski MJ, Froenicke L, Baysac KC, Billings NC, Leutenegger CM, Levy AM, Longeri M, Niini T, Ozpinar H, Slater MR, Pedersen NC, Lyons LA. The ascent of cat breeds: genetic evaluations of breeds and worldwide random-bred populations. Genomics. 2008;91(1):12-21. Epub 2007/12/07. doi: 10.1016/j.ygeno.2007.10.009. PubMed PMID: 18060738; PubMed Central PMCID: PMC2267438.

Cat Genomics

Li G, Hillier LW, Grahn RA, Zimin AV, David VA, Menotti-Raymond M, Middleton R, Hannah S, Hendrickson S, Makunin A, O'Brien SJ, Minx P, Wilson RK, Lyons LA, Warren WC, Murphy WJ. A High-Resolution SNP Array-Based Linkage Map Anchors a New Domestic Cat Draft Genome Assembly and Provides Detailed Patterns of Recombination. G3 (Bethesda). 2016 Jun 1;6(6):1607-16. doi:10.1534/g3.116.028746. PubMed PMID: 27172201; PubMed Central PMCID: PMC4889657.

Bertolini F, Gandolfi B, Kim ES, Haase B, Lyons LA, Rothschild MF. Evidence of selection signatures that shape the Persian cat breed. Mamm Genome. 2016 Apr;27(3-4):144-55. doi: 10.1007/s00335-016-9623-1. Erratum in: Mamm Genome. 2016 Apr;27(3-4):156-7. PubMed PMID: 26956354.

Alhaddad H, Zhang C, Rannala B, Lyons LA. A Glance at Recombination Hotspots in the Domestic Cat. PLoS One. 2016 Feb 9;11(2):e0148710. doi:10.1371/journal.pone.0148710. PubMed PMID: 26859385; PubMed Central PMCID:PMC4747544.

Montague MJ, Li G, Gandolfi B, Khan R, Aken BL, Searle SM, Minx P, Hillier LW, Koboldt DC, Davis BW, Driscoll CA, Barr CS, Blackistone K, Quilez J, Lorente-Galdos B, Marques-Bonet T, Alkan C, Thomas GW, Hahn MW, Menotti-Raymond M, O'Brien SJ, Wilson RK, Lyons LA, Murphy WJ, Warren WC. Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication. Proceedings of the National Academy of Sciences of the United States of America. 2014. doi: 10.1073/pnas.1410083111. PubMed PMID: 25385592.

Alhaddad H, Khan R, Grahn RA, Gandolfi B, Mullikin JC, Cole SA, Gruffydd-Jones TJ, Haggstrom J, Lohi H, Longeri M, Lyons LA. Extent of linkage disequilibrium in the domestic cat, Felis silvestris catus, and its breeds. PloS one. 2013;8(1):e53537. Epub 2013/01/12. doi: 10.1371/journal.pone.0053537. PubMed PMID: 23308248; PubMed Central PMCID: PMC3538540.

Bach LH, Gandolfi B, Grahn JC, Millon LV, Kent MS, Narfstrom K, Cole SA, Mullikin JC, Grahn RA, Lyons LA. A high-resolution 15,000(rad) radiation hybrid panel for the domestic cat. Cytogenet Genome Res. 2012;137(1):7-14. Epub 2012/07/11. doi: 10.1159/000339416. PubMed PMID: 22777158.

Wildcats

Mattucci F, Oliveira R, Lyons LA, Alves PC, Randi E. European wildcat populations are subdivided into five main biogeographic groups: consequences of Pleistocene climate changes or recent anthropogenic fragmentation? Ecol Evol. 2015 Dec 7;6(1):3-22. doi: 10.1002/ece3.1815. PubMed PMID: 26811770; PubMed Central PMCID: PMC4716505.

Oliveira R, Randi E, Mattucci F, Kurushima JD, Lyons LA, Alves PC. Toward a genome-wide approach for detecting hybrids: informative SNPs to detect introgression between domestic cats and European wildcats (Felis silvestris). Heredity (Edinb). 2015 Sep;115(3):195-205. doi: 10.1038/hdy.2015.25. PMID: 26103945

Mattucci F, Oliveira R, Bizzarri L, Vercillo F, Anile S, Ragni B, Lapini L, Sforzi A, Alves PC, Lyons LA, Randi E. Genetic structure of wildcat (Felis silvestris) populations in Italy. Ecology and Evolution. 2013;3(8):2443-58. Epub 22 JUN 2013. doi: 10.1002/ece3.569. PubMed PMID: 12969463.

 

 

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