Department of Veterinary Pathobiology

Shuping Zhang

  • BVM, Veterinary Medicine and Surgery, Shanxi Agricultural University, Taigu, China     
  • MS. Veterinary Anatomy and Histology, Northwestern Agricultural University, Yanglin, China  
  • PhD, Microbiology, Kansas State University, Manhattan, KS
  • Postdoc, Texas A&M University, College Station, TX         
  • Diplomat, American Association Of Veterinary Microbiologists (Bacteriology/Mycology)

Building Address: W138 Veterinary Medicine Building/D105 VMDL
Phone Number: (573) 882-6811

VMDL Website:

Research Emphasis: Bacteriology, Infectious Disease, Microbiology, Molecular Diagnostics, Emerging & Zoonotic Diseases

Non-typhoidal salmonellosis is the second most common cause of food-borne illness associated with bacteria, viruses, and parasites in the US. Each year more than 1.4 million cases with approximately 600 deaths are reported.  Salmonella enterica serovar Enteritidis (SE) and Typhimurium are major etiologic agents of non-typhoid salmonellosis in the United States. SE persistently and silently colonizes the intestinal and reproductive tract of laying hens, resulting in contaminated poultry products. The consumption of contaminated food and water has been identified as a significant risk factor for human salmonellosis.

The research in my laboratory is focused on the pathogenesis and diagnosis of Salmonella infection in different host species. Currently, there are three lines of research in my laboratory, including 1) characterizing SE virulence genes that contribute to persistent colonization of the host, 2) characterizing  host antimicrobial peptides, 3) developing PCR-based assays and Micro-electromechanical systems (MEMS)-based biosensing technology for rapid detection of bacterial pathogens in clinical and food samples.

Besides research, my passion lies in veterinary diagnostic service and administration. I direct the MU Veterinary Medical Diagnostic Laboratory (VMDL) which is an all species full service diagnostic laboratory accredited by American Association of Veterinary Laboratory Diagnosticians. The VMDL has 10 service sections that test animal specimens for rapid disease diagnosis. The VMDL offers unique opportunities for students or trainees to gain hands-on experience in the following areas: anatomical pathology, clinical pathology, clinical microbiology, clinical serology, clinical virology, histology and immunohistochemistry, molecular diagnostics, and toxicology. 

Selected Publications in Past Five Years:


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