Areas of Research

Bacteriology
Deborah Anderson: Yersinia pestis; Innate Immunity; Transmission; Biocontainment

Michael Calcutt: Mycoplasmas; Animal Pathogens; Mobile Genetic Elements; Surface Antigens; Horizontal Gene Transfer

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

William H. Fales: Veterinary Diagnostic Bacteriology & Mycology; Johne’s Disease; Antimicrobial Susceptibility Testing & Rapid Detection of Infectious Disease Agents

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Thomas Reilly: Acid Phosphatase; Phosphomonoesterase; Class C Phosphatases; Francisella; Histidine Acid Phosphatases

George C. StewartBacillus anthracis/Clostridium difficile Spore Maturation; Virulence Gene Regulation in Staphylococci; Spore Platforms for Vaccine Development & Bioremediation

Guoquan Zhang: Host-Bacterial Pathogen-Interaction; Development of Vaccines against Q Fever; Pathogenesis of Coxiella burnetii; Mechanisms of Host Immunity against Aerosolized Intracellular Bacterial Pathogens; Aerosol Infection Animal Models

Shuping Zhang: Bacteria; Defensins; Diagnostics; Salmonella; Surveillance

|return to menu|

 

Cell Biology
Heide Schatten: Cell & Molecular Biology; Cell Cycle; Cytoskeleton; Centrosomes; Microtubules; Microscopy; Cancer Biology; Reproductive Biology; Developmental Biology; Space Biology

|return to menu|

 

Clinical Pathology
Linda M. Berent: Oncology; Hematology; SoTL; Teaching; Learning

Maryln S. Whitney: Blood Parasites; Lipid Metabolism; Teaching Methodology

Charles Wiedmeyer: Comparative Medicine; Clinical Pathology; Renal; Clinical chemistry; Glucose Monitoring

|return to menu|

 

Comparative Medicine
James M. Amos-Landgraf: Comparative Medicine; Gene Expression & Control; Molecular Genetics & Genomic Analysis; Translational Medicine

Yuksel Agca: Reproduction; Cryobiology; Comparative Medicine; Transgenic

Elizabeth C. Bryda: Embryonic stem cells; Kidney Disease; Deafness; Comparative Medicine; Rodent Genetics

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

Timothy J. Evans: Endocrine Disruption; Ergot Alkaloids; Mycotoxins; Porcine Models; Reproduction; Veterinary Toxicology

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Gary S. Johnson: Molecular Genetics; Whole Genome Sequencing; Genome-wide Association Mapping; Heritable Canine Diseases; Neurodevelopmental & Neurodegenerative Diseases

Kei Kuroki: Osteoarthritis; Comparative Orthopaedic; Joint Pathology

Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Hongsheng Men: Reproductive Physiology; Stem Cell Biology; Rodent Models

Charles Wiedmeyer: Comparative Medicine; Clinical Pathology; Renal; Clinical chemistry; Glucose Monitoring

|return to menu|

 

Cytoskeletal Regulation
Heide Schatten: Cell & Molecular Biology; Cell Cycle; Cytoskeleton; Centrosomes; Microtubules; Microscopy; Cancer Biology; Reproductive Biology; Developmental Biology; Space Biology

|return to menu|

 

Disaster Preparedness & Response Planning
Catherine Vogelweid: Disaster Preparedness & Response Planning, Disaster-resistant Facilities Construction

|return to menu|

 

Gene Expression & Control
James M. Amos-Landgraf: Comparative Medicine; Gene Expression & Control; Molecular Genetics & Genomic Analysis; Translational Medicine

Elizabeth C. Bryda: Embryonic Stem Cells; Kidney Disease; Deafness; Comparative Medicine; Rodent Genetics

Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Monique A. Lorson: Spinal Muscular Atrophy; Neurodegenerative Disease; Animal Models of Human Disease; Swine; Therapeutic Delivery

Alpana Ray: Z-DNA Conformation in Neoplastic Diseases; Epigenetic Modulation in Gene Regulation; Molecular Mechanisms of Gene Expression During Chronic Inflammation; Inflammation in Neoplastic Diseases; Regulation of Gene Expression in Pathogenesis; Transcriptional and Post-Transcriptional Control of Gene Expression.

Bimal K. Ray: Inflammation; Arthritis; Cancer; Gene Regulation; Novel Therapeutics

|return to menu|

 

Gene Therapy
Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Monir Shababi: Adeno-Associated Virus (AAV; Spinal Muscular Atrophy (SMA); Spinal Muscular Atrophy with Respiratory Distress (SMARD1; Gene Therapy

|return to menu|

 

Immunology
Jeffrey J. Adamovicz: Vaccine Development; Animal Model Development; Study of Zoonotic Disease; Biocontainment Experimentation; Host-Pathogen Interactions

Charles R. Brown: Innate Immunity; Lyme disease; Borrelia burgdorferi; Arthritis; Eicosanoids

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats, Laboratory Animal Medicine

Solomon “Wole” Odemuyiwa: Immunomodulation by Toxins & Nutraceuticals; Mechanisms of Mediator Release from Immune Cells; Molecular Diagnostics; Molecular Epidemiology & New Virus Discovery; Viral Immune Escape Mechanisms

Jerod Skyberg: Biodefense; Immunotherapy; Innate Immunity

Guoquan Zhang: Host-Bacterial Pathogen-Interaction; Development of Vaccines against Q Fever; Pathogenesis of Coxiella burnetii; Mechanisms of Host Immunity against Aerosolized Intracellular Bacterial Pathogens; Aerosol Infection Animal Models

|return to menu|

 

Infectious Disease
Jeffrey J. Adamovicz: Vaccine Development; Animal Model Development; Study of Zoonotic Disease; Biocontainment Experimentation; Host-Pathogen Interactions

Deborah Anderson: Yersinia pestis; Innate Immunity; Transmission; Biocontainment

Paul Anderson: Animal Models of Infectious Disease; Biocontainment; Aerosol Biology

Brenda T. Beerntsen: Mosquito-Parasite Interactions; Mosquito Immunity; Parasites; Malaria; Lymphatic Filariasis

Charles R. Brown: Innate Immunity; Lyme disease; Borrelia burgdorferi; Arthritis; Eicosanoids

Michael Calcutt: Mycoplasmas; Animal Pathogens; Mobile Genetic Elements; Surface Antigens; Horizontal Gene Transfer

Craig L. Franklin: Helicobacter, Inflammatory Bowel Disease, Genetically-engineered Mice, Genetically-engineered Rats, Laboratory Animal Medicine

Alexander W.E. Franz: Arbovirology; Genetic Manipulation of Mosquitoes; Innate Immunity

Thomas Reilly: Acid Phosphatase; Phosphomonoesterase; Class C Phosphatases; Francisella; Histidine Acid Phosphatases

Jerod Skyberg: Biodefense; Immunotherapy; Innate Immunity

George C. Stewart: Bacillus anthracis/Clostridium difficile Spore Maturation; Virulence Gene Regulation in Staphylococci; Spore Platforms for Vaccine Development & Bioremediation

Guoquan Zhang: Host-Bacterial Pathogen-Interaction; Development of Vaccines against Q Fever; Pathogenesis of Coxiella burnetii; Mechanisms of Host Immunity against Aerosolized Intracellular Bacterial Pathogens; Aerosol Infection Animal Models

Shuping Zhang: Bacteria; Defensins; Diagnostics; Salmonella; Surveillance

|return to menu|

 

Inflammatory Diseases
Charles R. Brown: Innate Immunity; Lyme disease; Borrelia burgdorferi; Arthritis; Eicosanoids

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Alpana Ray: Z-DNA Conformation in Neoplastic Diseases; Epigenetic Modulation in Gene Regulation; Molecular Mechanisms of Gene Expression During Chronic Inflammation; Inflammation in Neoplastic Diseases; Regulation of Gene Expression in Pathogenesis; Transcriptional and Post-Transcriptional Control of Gene Expression.

Bimal K. Ray: Inflammation; Arthritis; Cancer; Gene Regulation; Novel Therapeutics

Jerod Skyberg: Biodefense; Immunotherapy; Innate Immunity

|return to menu|

 

Microbiology
Deborah Anderson: Yersinia pestis; Innate Immunity; Transmission; Biocontainment

Brenda T. Beerntsen: Mosquito-Parasite Interactions; Mosquito Immunity; Parasites; Malaria; Lymphatic Filariasis

Michael Calcutt: Mycoplasmas; Animal Pathogens; Mobile Genetic Elements; Surface Antigens; Horizontal Gene Transfer

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

William H. Fales: Veterinary Diagnostic Bacteriology & Mycology; Johne’s Disease; Antimicrobial Susceptibility Testing & Rapid Detection of Infectious Disease Agents

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Thomas Reilly: Acid Phosphatase; Phosphomonoesterase; Class C Phosphatases; Francisella; Histidine Acid Phosphatases

Jerod Skyberg: Biodefense; Immunotherapy; Innate Immunity

George C. Stewart: Bacillus anthracis/Clostridium difficile Spore Maturation; Virulence Gene Regulation in Staphylococci; Spore Platforms for Vaccine Development & Bioremediation

Guoquan Zhang: Host-Bacterial Pathogen-Interaction; Development of Vaccines against Q Fever; Pathogenesis of Coxiella burnetii; Mechanisms of Host Immunity against Aerosolized Intracellular Bacterial Pathogens; Aerosol Infection Animal Models

Shuping Zhang: Bacteria; Defensins; Diagnostics; Salmonella; Surveillance

|return to menu|

 

Microscopy
Heide Schatten: Cell &Molecular Biology; Cell Cycle; Cytoskeleton; Centrosomes; Microtubules; Microscopy; Cancer Biology; Reproductive Biology; Developmental Biology; Space Biology

|return to menu|

 

Molecular Diagnostics
Jeffrey J. Adamovicz: Vaccine Development; Animal Model Development; Study of Zoonotic Disease; Biocontainment Experimentation; Host-Pathogen Interactions

Elizabeth C. Bryda: Embryonic stem cells; Kidney Disease; Deafness; Comparative Medicine; Rodent Genetics

Gary S. Johnson: Molecular Genetics; Whole Genome Sequencing; Genome-wide Association Mapping; Heritable Canine Diseases; Neurodevelopmental & Neurodegenerative Diseases

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Solomon “Wole” Odemuyiwa: Immunomodulation by Toxins & Nutraceuticals; Mechanisms of Mediator Release from Immune Cells; Molecular Diagnostics; Molecular Epidemiology & New Virus Discovery; Viral Immune Escape Mechanisms

Thomas Reilly: Acid Phosphatase; Phosphomonoesterase; Class C Phosphatases; Francisella; Histidine Acid Phosphatases

Shuping Zhang: Bacteria; Defensins; Diagnostics; Salmonella; Surveillance

|return to menu|

 

Molecular Genetics & Genomic Analysis
James M. Amos-Landgraf: Comparative Medicine; Gene Expression & Control; Molecular Genetics & Genomic Analysis; Translational Medicine

Elizabeth C. Bryda: Embryonic stem cells; Kidney Disease; Deafness; Comparative Medicine; Rodent Genetics

Michael Calcutt: Mycoplasmas; Animal Pathogens; Mobile Genetic Elements; Surface Antigens; Horizontal Gene Transfer

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

Alexander W.E. Franz: Arbovirology; Genetic Manipulation of Mosquitoes; Innate Immunity

Gary S. Johnson: Molecular Genetics; Whole Genome Sequencing; Genome-wide Association Mapping; Heritable Canine Diseases; Neurodevelopmental & Neurodegenerative Diseases

Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Monique A. Lorson: Spinal Muscular Atrophy; Neurodegenerative Disease; Animal Models of Human Disease; Swine; Therapeutic Delivery

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Alpana Ray: Z-DNA Conformation in Neoplastic Diseases; Epigenetic Modulation in Gene Regulation; Molecular Mechanisms of Gene Expression During Chronic Inflammation; Inflammation in Neoplastic Diseases; Regulation of Gene Expression in Pathogenesis; Transcriptional and Post-Transcriptional Control of Gene Expression.

Bimal K. Ray: Inflammation; Arthritis; Cancer; Gene Regulation; Novel Therapeutics

|return to menu|

 

Neurodegenerative Diseases
Gary S. Johnson: Molecular Genetics; Whole Genome Sequencing; Genome-wide Association Mapping; Heritable Canine Diseases; Neurodevelopmental & Neurodegenerative Diseases

Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Monique A. Lorson: Spinal Muscular Atrophy; Neurodegenerative Disease; Animal Models of Human Disease; Swine; Therapeutic Delivery

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Monir Shababi : Adeno-Associated Virus (AAV; Spinal Muscular Atrophy (SMA); Spinal Muscular Atrophy with Respiratory Distress (SMARD1; Gene Therapy

|return to menu|

 

Parasitology
Brenda T. Beerntsen: Mosquito-Parasite Interactions; Mosquito Immunity; Parasites; Malaria; Lymphatic Filariasis

Roger W. (Bill) Stich: Biology of Ticks & Tick-Borne Pathogens; Immunology & Pathology of Tick-Borne Diseases; Cellular & Molecular Interface of Tick-Pathogen-Host Interactions; Immunology & Cellular Microbiology of Obligate Intracellular Bacterial & Protozoal Parasites

|return to menu|

 

Pathology

Chantelle C. Bozynski

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Gayle C. Johnson: Diagnostic Veterinary Pathology; Veterinary Neuropathology; Rickettsioses; Animal Models; Quantitative Pathology

Dae Young Kim: Dermatopathology; Diagnostic Pathology; Infectious Disease

Kei Kuroki: Osteoarthritis; Comparative Orthopaedic; Joint Pathology

W. Jefferson Mitchell, Jr.,:

Daniel P. Shaw: Veterinary Pathology; Poultry; Food Animal; Infectious Diseases

Fred Williams III

|return to menu|

 

Reproductive Biology
Yuksel Agca
: Reproduction; Cryobiology; Comparative Medicine; Transgenic

Timothy J. Evans: Endocrine Disruption; Ergot Alkaloids; Mycotoxins; Porcine Models; Reproduction; Veterinary Toxicology

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Hongsheng Men : Reproductive Physiology; Stem Cell Biology; Rodent Models

|return to menu|

 

Toxicology
Paul Anderson: Animal Models of Infectious Disease; Biocontainment; Aerosol Biology

Stan W. Casteel: Risk-assessment; Superfund-contaminants; Toxicology; Bioavailability; Metals; Biokinetics

Timothy J. Evans: Endocrine Disruption; Ergot Alkaloids; Mycotoxins; Porcine Models; Reproduction; Veterinary Toxicology

|return to menu|

 

Translational Medicine
James M. Amos-Landgraf: Comparative Medicine; Gene Expression & Control; Molecular Genetics & Genomic Analysis; Translational Medicine

Yuksel Agca: Reproduction; Cryobiology; Comparative Medicine; Transgenic

Elizabeth C. Bryda: Embryonic stem cells; Kidney Disease; Deafness; Comparative Medicine; Rodent Genetics

Aaron Ericsson: Gut Microbiota; Metagenomics; Next-generation Sequencing; Mucosal Homeostasis; Colorectal Cancer

Craig L. Franklin: Helicobacter; Inflammatory Bowel Disease; Genetically-engineered Mice; Genetically-engineered Rats; Laboratory Animal Medicine

Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

Leslie Lyons: Feline Inherited Diseases and Traits; Feline Population Dynamics; Genome-wide Association Mapping; Whole Genome Sequencing

Hongsheng Men : Reproductive Physiology; Stem Cell Biology; Rodent Models

|return to menu|

 

Vector-borne, Emerging & Zoonotic Diseases
Jeffrey J. Adamovicz: Vaccine Development; Animal Model Development; Study of Zoonotic Disease; Biocontainment Experimentation; Host-Pathogen Interactions

Deborah Anderson: Yersinia pestis; Innate Immunity; Transmission; Biocontainment

Paul Anderson: Animal Models of Infectious Disease; Biocontainment; Aerosol Biology

Brenda T. Beerntsen: Mosquito-Parasite Interactions; Mosquito Immunity; Parasites; Malaria; Lymphatic Filariasis

Charles R. Brown: Innate Immunity; Lyme disease; Borrelia burgdorferi; Arthritis; Eicosanoids

Michael Calcutt: Mycoplasmas; Animal Pathogens; Mobile Genetic Elements; Surface Antigens; Horizontal Gene Transfer

Alexander W.E. Franz: Arbovirology; Genetic Manipulation of Mosquitoes; Innate Immunity

Solomon “Wole” Odemuyiwa: Immunomodulation by Toxins & Nutraceuticals; Mechanisms of Mediator Release from Immune Cells; Molecular Diagnostics; Molecular Epidemiology & New Virus Discovery; Viral Immune Escape Mechanisms

Thomas Reilly: Acid Phosphatase; Phosphomonoesterase; Class C Phosphatases; Francisella; Histidine Acid Phosphatases

Jerod Skyberg: Biodefense; Immunotherapy; Innate Immunity

George C. Stewart: Bacillus anthracis/Clostridium difficile Spore Maturation; Virulence Gene Regulation in Staphylococci; Spore Platforms for Vaccine Development & Bioremediation

Roger W. (Bill) Stich: Biology of Ticks & Tick-Borne Pathogens; Immunology & Pathology of Tick-Borne Diseases; Cellular & Molecular Interface of Tick-Pathogen-Host Interactions; Immunology & Cellular Microbiology of Obligate Intracellular Bacterial & Protozoal Parasites

Guoquan Zhang: Host-Bacterial Pathogen-Interaction; Development of Vaccines against Q Fever; Pathogenesis of Coxiella burnetii; Mechanisms of Host Immunity against Aerosolized Intracellular Bacterial Pathogens; Aerosol Infection Animal Models

|return to menu|

 

Virology
Christian L. Lorson: Molecular Genetics; Gene Therapy; Drug Development; RNA Processing; Alternative Splicing; Neurodegeneration; Spinal Muscular Atrophy; Animal Models of Disease

W. Jefferson Mitchell, Jr.,:

Solomon “Wole” Odemuyiwa: Immunomodulation by Toxins & Nutraceuticals; Mechanisms of Mediator Release from Immune Cells; Molecular Diagnostics; Molecular Epidemiology & New Virus Discovery; Viral Immune Escape Mechanisms

Monir Shababi : Adeno-Associated Virus (AAV; Spinal Muscular Atrophy (SMA); Spinal Muscular Atrophy with Respiratory Distress (SMARD1; Gene Therapy

|return to menu|


 

Faculty Spotlight

Alexander W.E. Franz

Alexander Franz, PhD won the 2014 award for best paper in the journal Insect Molecular Biology. Sponsored by the Royal Entomological Society, the award recognizes the best paper over a two-year period. The paper, “Transgene-mediated suppression of the RNA interference pathway in Aedes aegypti interferes with gene silencing and enhances Sindbis virus and dengue virus type 2 replication”. More recently, his laboratory was the first to report the use of CRISPR/Cas9 for genome editing in the mosquito vector, Aedes aegypti (PLoS One. 2015 Mar 27;10(3):e0122353. doi: 10.1371/journal.pone.0122353. eCollection 2015).

©2012 Curators of the University of Missouri
An equal opportunity/ADA institution

 

 

University of Missouri College of Veterinary Medicine University of Missouri